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Understanding the Molecular Roots of Alzheimer’s Disease

By Jennifer Thompson, 9:00 am on

Alzheimer’s disease is a neurological condition responsible for more than half of all dementia cases in the United States. It causes memory loss, confusion, anxiety, and several other cognitive conditions that are difficult to treat in seniors, and it can also make the job of Nashville, TN, home care professionals more challenging. Here’s what you need to know about the root cause of Alzheimer’s in aging adults.

Molecular Chemistry of Alzheimer’s Disease

Researchers at the Washington University School of Medicine have recently studied the molecular aspects of Alzheimer’s disease. Experts confirmed this form of dementia might be caused by a mutation in the TREM2 protein. Under normal conditions, the TREM2 enzyme clears cellular waste in the brain. A change in the protein’s molecular composition can lead to the buildup of toxic substances in the brain, such as amyloid beta amino acids. These plaque-like amino acids show up in high concentrations in the brains of seniors with dementia. 

How Can TREM2 Treat Alzheimer’s Disease?

TREM2 can treat Alzheimer’s disease by initiating the removal of wastes from nerve cells. However, scientists have not yet found an effective way to introduce this protein into the human body. Sophisticated biotechnology techniques will have to be used to somehow synthesize this molecule in bulk for medical purposes. Another challenge would be to make TREM2 available in an edible form such as a capsule, tablet, or pill.

Other Interesting Findings on TREM2

Besides having the potential to treat dementia and Alzheimer’s, TREM2 might also be useful for managing Parkinson’s disease. Scientists at the Washington University School of Medicine have confirmed a mutation in the protein’s molecular structure is directly linked to an increased risk for Parkinson’s disease.

Although a cure for Alzheimer’s may be found in the distant future, getting regular exercise and focusing on proper nutrition can help keep seniors keep memory loss at bay in the present. Help your aging loved one slow down cognitive decline with the reliable Cognitive Therapeutics Method at Home Care Assistance. The program helps delay the onset of dementia through a series of diet, exercise, and social stimulation plans. To learn more about this program, and to hire an experienced Alzheimer’s caregiver in Nashville, TN, for your loved one, give us a call at (615) 656-4999.